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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Teniposide:
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ACUTE EXPOSURE INFORMATION
- WITH THERAPEUTIC USE
- Myelosuppression is the dose-limiting toxicity and a frequent occurrence with teniposide therapy. Other adverse effects that may commonly occur with teniposide therapy include nausea, vomiting, mucositis, and diarrhea. Hypersensitivity reactions, consisting of chills, fever, tachycardia, flushing, bronchospasm, dyspnea, and blood pressure changes (hypotension or hypertension), and transient hypotension following rapid intravenous administration have been infrequently reported in pediatric patients.
- WITH POISONING/EXPOSURE
- Teniposide overdose information is limited. Severe myelosuppression is the anticipated effect following overdose. Hypotension, metabolic acidosis and somnolence have been reported after 3 to 5 tomes the usual therapeutic dose.
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