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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Pramlintide:
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ACUTE EXPOSURE INFORMATION
- WITH THERAPEUTIC USE
- The most frequently reported adverse effects, following therapeutic administration of pramlintide, include nausea, vomiting, anorexia, and headache.
- Concomitant administration of pramlintide with one or more antidiabetic agents (eg, insulin, sulfonylureas) increases the risk of hypoglycemia. Severe hypoglycemia associated with pramlintide will generally occur within 3 hours after pramlintide administration.
- WITH POISONING/EXPOSURE
- Pramlintide overdose information is limited. Severe nausea, vomiting, diarrhea, vasodilatation, and dizziness were reported in healthy volunteers following administration of single 10-mg doses.
- Hypoglycemia is not expected after administration of pramlintide alone, but may develop if pramlintide is administered with insulin or other hypoglycemic agents.
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