RightAnswer Knowledge Solutions provides access to hundreds of data sources. Our premier and proprietary sources include fully-researched documents from well-established experts in the chemical and HazMat fields.
A search in our system for this chemical would return results – all in one place -- in the following categories from the listed data sources.
- Chemical Identification
- Environmental Hazards
- First Aid/Medical Treatment
- Handling/Storage/Shipping/Waste Management
- Personal Protection
- Physical Hazards/Corrective Response Actions
- Physical/Chemical Properties
- Report Abstracts and Studies
- Reproductive Risk
- Toxicology/Health Hazards/Exposure
|Example of Acute Exposure data from MEDITEXT.|
RightAnswer Proprietary Data Sources:
Other Government Links Searched via RegsKnowledge:
State Environmental Regulations
Example Content from MEDITEXT for Memantine:
Please note: this is an extract of information from a larger document. Full document and details are available by subscription.
ACUTE EXPOSURE INFORMATION
- USES: Memantine is indicated in the treatment of moderate to severe dementia of the Alzheimer's type.
- PHARMACOLOGY: Memantine hydrochloride is a low to moderate affinity, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist which binds to NMDA receptor-operated cation channels. Memantine also blocks the 5-hydroxytryptamine-3 receptor (at a potency similar to the NMDA receptor) and nicotinic acetylcholine receptors (at one-sixth to one-tenth the potency). However, memantine has low to negligible affinity for gamma-aminobutyric acid, benzodiazepine, dopamine, adrenergic, histamine, and glycine receptors and for voltage-dependent calcium, sodium, or potassium channels.
- EPIDEMIOLOGY: Overdose is rare.
- WITH THERAPEUTIC USE
- The following adverse effects have been reported following therapeutic use of memantine (less than 6%): Headache, diarrhea, dizziness, somnolence, fatigue, muscle weakness, akathisia, agitation, increased motor activity, insomnia, tachycardia, bradycardia, hypertension, constipation, seizures, and psychosis.
- WITH POISONING/EXPOSURE
- MILD TO MODERATE OVERDOSE: Effects can include agitation, bradycardia, confusion, dizziness, hypertension, lethargy, restlessness, unsteady gait, vertigo, vomiting and weakness.
- SEVERE OVERDOSE: Can cause nystagmus, hallucinations, psychosis, seizures, and coma.
© 2011-2021 RightAnswer.com, Inc. and/or its licensors. All rights reserved. No claim to original U.S. Govt. works.