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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Formothion:
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ACUTE EXPOSURE INFORMATION
- Formothion is an organophosphate compound. The following are symptoms from organophosphates in general, which are due to the anticholinesterase activity of this class of compounds. All of these effects may not be documented for formothion, but could potentially occur in individual cases.
- In addition to typical anticholinesterase poisoning symptoms, formothion caused contact sensitization dermatitis with papules, erythema, and edema in one worker following direct skin contact. Irritation was not seen when formothion was instilled directly into the eyes of rabbits.
- MUSCARINIC (PARASYMPATHETIC) EFFECTS may include bradycardia, bronchospasm, bronchorrhea, salivation, lacrimation, diaphoresis, vomiting, diarrhea, and miosis. NICOTINIC (SYMPATHETIC AND MOTOR) EFFECTS may include tachycardia, hypertension, fasciculations, muscle cramps, weakness, and RESPIRATORY PARALYSIS. CENTRAL EFFECTS may include CNS depression, agitation, confusion, delirium, coma, and seizures.
- Children may exhibit different predominant signs and symptoms than adults: CNS depression, stupor, flaccidity, dyspnea, and coma are the most common signs in children.
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