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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Urea:
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ACUTE EXPOSURE INFORMATION
- ANIMAL STUDIES - In sheep and cattle, clinical effects included pronounced muscle fasciculations, trembling, grinding teeth, dysrhythmias, ataxia, lateral recumbency, anuria, dry mouth, frothy salivation, dyspnea, bloating, abdominal pain, regurgitation, hyperesthesia, mydriasis and convulsions. The primary cause of death was respiratory arrest. Laboratory examination showed increased glucose, ammonia and urea levels.
- WITH THERAPEUTIC USE
- Adverse effects include nausea, vomiting, dizziness, disorientation, drowsiness, diuresis, hyponatremia, hypokalemia, and confusion. Urea's systemic toxicity is similar to that of mannitol.
- WITH POISONING/EXPOSURE
- Urea is considered a mild to moderate intoxicant and a mild irritant. Exposure causes erythema of eyes and skin. Urea's systemic toxicity is similar to that of mannitol. Massive occupational exposure to carbamide produced persistent respiratory insufficiency.
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