RightAnswer Knowledge Solutions Search Results for Dichlorophenylarsine

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ACUTE EXPOSURE INFORMATION

  1. Dichlorophenylarsine has been used as a solvent and military agent. It decomposes upon contact with water to form HYDROCHLORIC ACID. It produces vomiting, lacrimation, and blisters, and can be fatal if absorbed through the lungs, skin, or gastrointestinal tract. Burns or severe irritation to the eyes, skin, and lungs with pulmonary edema would be expected to occur.
  1. Chronic exposure to dichlorophenylarsine has been reported to produce contact dermatitis. Presumably chronic exposures at doses too low to produce irritative effects could produce arsenic poisoning. Thymic atrophy occurred in rats given dichlorophenylarsine in the diet.
  1. This review is based upon the properties of lacrimators, vesicants, and arsenic. Effects attributed specifically to dichlorophenylarsine are identified.
  1. Acute arsenic poisoning can occur with doses as low as 20 mg in an adult. Symptoms of acute arsenic poisoning include metallic or garlic taste, vomiting, abdominal pain, dysphagia, and watery or bloody diarrhea. Dehydration, intense thirst, fluid-electrolyte disturbances and hypovolemia are common. Hypotension, tachycardia, cardiac dysrhythmias and EKG abnormalities, toxic delerium and encephalopathy, peripheral neuropathy, and liver and kidney damage may also occur. Hemolysis, pancytopenia, anemia, and seizures have been caused by acute or chronic exposure to arsenic.
  1. Chronic occupational exposure to arsenic has been associated with hoarse voice, nasal irritation and possible perforation of the nasal septum, irritation of eyes, skin, and mucous membranes, and rarely, cirrhosis of the liver. Nausea and vomiting and ulceration of the wrist and scrotal skin, lips, and nostrils may develop with exposure to dust or vapor. Systemic arsenic poisoning from occupational exposure is uncommon.
  1. Arsenic exposure has been linked with cancers of the lungs, lymph glands, bone marrow, bladder, kidney, prostate, and liver.
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