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|Example of Acute Exposure data from MEDITEXT.|
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Example Content from MEDITEXT for Deferasirox:
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ACUTE EXPOSURE INFORMATION
- WITH THERAPEUTIC USE
- Adverse effects reported with the use of deferasirox included the following: increased serum creatinine, proteinuria, acute renal failure, increased ALT, drug-induced hepatitis, cytopenias (agranulocytosis, neutropenia, thrombocytopenia) rash, urticaria, abdominal pain, nausea, vomiting, diarrhea, back and joint pain, headache, fatigue.
- WITH POISONING/EXPOSURE
- Hepatitis was reported in one patient who received 2 to 3 times the prescribed dose of deferasirox over a period of several weeks. In iron overloaded beta-thalassemic patients, single doses up to 80 mg/kg have been tolerated with nausea and diarrhea noted. Single doses up to 40 mg/kg were tolerated in healthy volunteers.
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