RightAnswer Knowledge Solutions Search Results for Cladribine

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ACUTE EXPOSURE INFORMATION

  1. WITH THERAPEUTIC USE
    1. Myelosuppression is the dose-limiting toxicity of cladribine. Its duration may be prolonged after discontinuation of therapy. Other adverse effects, frequently reported with cladribine therapy, include fever, fatigue, nausea, rash, and headache.
  1. WITH POISONING/EXPOSURE
    1. Cladribine overdose information is limited. Severe neurotoxicity (paraparesis/quadriparesis), acute nephrotoxicity, severe myelosuppression, and fatal systemic bacterial or fungal infections have been associated with very high doses.
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