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ACUTE EXPOSURE INFORMATION
- Dimethyl sulfate (DMS) is extremely irritating to the eyes, skin, and mucous membranes. Toxicity is most common following inhalation of vapors or dermal exposure. Symptoms may be delayed for several hours after inhalation or dermal exposure. several hours.
- Presenting symptoms following vapor exposure may include eye pain, photophobia, lacrimation, blurred vision, corneal edema, and angioneurotic edema, followed by pharyngolaryngeal inflammation, dysphonia, aphonia, dysphagia, productive cough, dyspnea, and cyanosis. Delayed pulmonary edema may occur. Other effects may include fever, delirium, seizures, coma, ECG changes, liver and kidney damage, hematuria, and albuminuria.
- Contact with the liquid can cause irritation with severe ocular and dermal chemical burns. Dermal exposures may have a 1 to 2 hour delay before onset of symptoms which may include severe local burn with redness, swelling, pain, and bleb formation.
- Oral exposure may result in nausea; vomiting; burns of the mouth, pharynx, and stomach; seizures; areflexia; cyanosis; pulmonary edema; and circulatory failure.
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