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ACUTE EXPOSURE INFORMATION
- Immediate irritant effects such as conjunctivitis, rhinitis, pharyngitis, bronchitis, lacrimation, blepharospasm conjunctival hyperemia, and upper respiratory tract irritation may occur after exposure to concentrations of 3 to 5 ppm.
- Severe pulmonary toxicity may develop after exposure to higher doses. Signs and symptoms of toxicity may be delayed, although rare, for 24 to 72 hours and include choking, chest tightness, severe dyspnea, pulmonary edema, cough, production of foaming bloody sputum, nausea, and anxiety. Cardiac failure has occasionally occurred as a complication of severe pulmonary edema.
- Exposure to a cumulative dose of 50 ppm x minutes may cause pulmonary edema; a dose of 150 ppm x min will probably cause pulmonary edema and a dose of 300 ppm x min is likely to be fatal.
- Brief exposure to 50 ppm or greater may be rapidly fatal. Prolonged exposure to low concentrations (e.g. 3 ppm for 170 min) can also be fatal. Exposure to concentrations less than 3 ppm may not be immediately accompanied by symptoms; delayed effects usually occur within 24 hrs of exposure.
- Chlorinated hydrocarbons (e.g., carbon tetrachloride, trichloroethylene, methylene chloride) in contact with a flame or very hot metal decompose to phosgene gas.
- Liquid phosgene is a frostbite hazard and has caused corneal opacification.
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