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ACUTE EXPOSURE INFORMATION

  1. Sulfur dioxide is classified as an irritant gas; it produces immediate and severe irritant effects after exposure. It is extremely irritating to skin and eyes and to the mucosa of the nasopharynx and respiratory tract.
  1. Inhalation produces choking, coughing, sneezing, rhinorrhea, wheezing, dyspnea, cyanosis, chest pain, tracheitis, bronchitis, nausea, vomiting, fatigue, bronchoconstriction, pneumonitis, laryngeal/glottal edema, upper airway edema or obstruction and increased airflow resistance; death may result from pulmonary edema, systemic acidosis or respiratory arrest.
  1. Exposure to levels of 400 to 500 ppm is considered immediately life-threatening. Obstructive and restrictive lung disease, reactive airway disease syndrome (RADS), or chronic bronchitis may develop in victims who survive exposure to high concentrations. RADS may persist for months to years after exposure. Asthmatics are particularly sensitive to the respiratory effects of sulfur dioxide.
  1. Sulfur dioxide is a corrosive irritant of the skin and eyes, although actual eye injury from the gas is rare. It causes smarting of the eyes, lacrimation and conjunctival irritation. Contact with moist skin produces increased adverse dermal effects. Serious skin and eye frostbite injury or burns may result from direct contact with liquefied sulfur dioxide. Corneal opacity, erosion or necrosis and ultimately blindness are possible consequences of eye exposure. Frostbite and chemical burns to the mouth can occur.
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