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• (1a alpha, 2a beta, 3 beta, 6 beta, 6a beta, 8aS*, 8b beta, 9R*)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-8H-1,5,7-trioxa-3,6-methanocyclopenta [ij]cycloprop[a]azulene-4,8[3H]dione, compd. with (1a alpha, 2a beta, 3 beta, 6 beta, /
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ACUTE EXPOSURE INFORMATION
- Picrotoxin is a type of central nervous system stimulant called an analeptic. There is little quantitative information on the effects of picrotoxin in humans except in its former role as an antidote to severe barbiturate poisoning.
- It may stimulate respiration, elevate blood pressure, increase or decrease temperature, induce cardiac dysrhythmias, and cause gastrointestinal distress.
- It has the potential to cause seizures and fatal respiratory paralysis in humans. Lethal doses have produced clonic/tonic seizures in animals.
- Adrenergic signs such as dilated and unresponsive pupils, salivation, and gastrointestinal hyperactivity have been seen in humans.
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