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• [Anti-Androgenic activity of phthalate esters (di(2-ethylhexyl) phthalate, di(n-butyl) phthalate, and butylbenzyl phthalate) in the rodent 10-day hershberger assay using immature castrated male rats]
• Adverse effects of antiandrogenic pesticides and toxic substances on reproductive development in the male.
• Age-Based Comparison of Di-(2-ethylhexyl) Pthalate (DEHP)-Induced Immunotoxicity in the Female Rat.
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ACUTE EXPOSURE INFORMATION

  1. The phthalates are generally considered to be of slight to moderate toxicity. Di(2-ethylhexyl) phthalate (DEHP) may be irritating to the eyes, skin, and mucous membranes. Mild gastric disturbances and diarrhea may occur following ingestion of larger doses. CNS depression may occur if large amounts of phthalate acid esters are absorbed. However DEHP is considered innocuous at small doses.
  1. DEHP has a low order of toxicity. At significant concentrations irritation of mucous membranes may occur. Ingestion of large amounts during an experiment resulted in mild gastric upset and diarrhea.
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