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ACUTE EXPOSURE INFORMATION
- INGESTION - Initial effects seen after ethylene dichloride (EDC) ingestion are gastrointestinal; vomiting is common. Cyanosis, dyspnea, and coma may be delayed in onset. In severe cases, CNS signs appear first within several hours of exposure, followed by a quiescent period. On the second day, oliguria and hepatic transaminasemia may develop. Subsequently, hepatorenal failure can occur over the next several days. Gastrointestinal bleeding may occur. Pulmonary edema may develop. Death may be due to cardiovascular, respiratory, or hepatorenal failure.
- Neurologic effects have been reported including headache, weakness, vertigo, tremor, and dizziness.
- INHALATION - Vapors may produce irritation of respiratory tract and conjunctiva, corneal clouding, CNS depression, and liver, kidney and adrenal gland impairment.
- DERMAL - Ethylene dichloride is a skin and severe eye irritant, and strong local irritant. The liquid is readily absorbed through the skin, thus systemic effects may occur.
- EYE - Contact with either the liquid or with high concentrations of vapor causes immediate discomfort with conjunctival hyperemia and slight corneal injury; corneal burns from splashes recover quickly with no scarring.
- When heated to decomposition, toxic fumes of carbon monoxide, carbon dioxide, hydrogen chloride gas, and phosgene are emitted.
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